Infectious disease researchers and clinicians have difficulty in formulating
queries that capture the kinds of questions they wish to pose. The taxonomy used to
describe micro-biological data is complex; this terminology also changes with time. As a
means for overcoming these difficulties, we have developed methods for efficiently
integrating semantic knowledge, stored in the form of thesauri (or more precisely,
ontologies) in ways that support efficient indexing of large databases. The goal of this
effort is to provide clinicians with the ability to express complex queries without
becoming experts on the underlying data model. Thus far, we have employed this technique
to index relational databases. We will soon adapt this method to support efficient indices
for sensor and scientific datasets.