| Comp-bio | High-performance computing for bioinformatics applications |
| Cyclone | A type-safe systems programming language based on C |
| DSSL | Distributed systems software laboratory |
| Dyninst | Runtime binary editing tools |
| Harmony | Automatic adaptation of applications at runtime |
| NICE | Cooperative internet applications |
| MENTER | Load-adaptive resource scheduling for routers, wide-area event notification protocols |
| MIND Lab | Maryland Information and Network Dynamics Lab |
| MISSL | Maryland Information System Security Lab |
| MediaNet | Distribution networks for streaming data |
| MoteFS | Wide-area, versioning file systems |
| P5 | Anonymous communication protocols that can withstand all passive attacks |
| SESF | Compositional framework for concurrent services and systems |
| Sigma | Detailed memory performance analysis tools |
| TerraDir | Peer-to-peer system organization and performance |
| Osubi | Object spaces for ubiquitous interaction |
| Z-iteration | Fast solution of time-dependent queueing systems |
